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E-AB-14846

CD27 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-14846
Additional Names:
CD 27,CD27,CD27 antigen,CD27 molecule,CD27L receptor,LPFS2,MGC20393,OTTHUMP00000238557,S152,T cell activation antigen CD27,T cell antivation antigen S152,T-cell activation antigen CD27,T14,TNFRSF 7,TNFRSF7,TNFSF7,Tp 55,Tp55,Tumor necrosis factor rece
Application:
IHC, WB
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human CD27
Uniprot:
P26842
Synonyms:
CD27 antigen;CD27L receptor;S152;S152. LPFS2;T cell activation antigen S152;T-cell activation antigen CD27;T14;TNFRSF7;Tp55;Tumor necrosis factor receptor superfamily member 7;tumor necrosis factor receptor superfamily, member 7
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Shipping Conditions:
Blue Ice