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E-AB-14771

ASB2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-14771
Additional Names:
Ankyrin repeat and SOCS box 2 containing protein,Ankyrin repeat and SOCS box containing 2,Ankyrin repeat and SOCS box containing protein 2,Ankyrin repeat and SOCS box containing protein 2a,Ankyrin repeat and SOCS box protein 2,Ankyrin repeat containing pr
Application:
IHC
Concentration:
0.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human ASB2
Uniprot:
Q96Q27
Synonyms:
ankyrin repeat and SOCS box protein 2;ankyrin repeat and SOCS box-containing protein 2a;ASB-2
Extra Details:
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Shipping Conditions:
Blue Ice