E-AB-14759
ACTN4 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14759
- Additional Names:
- ACTN 4,ACTN4,Actinin alpha 4,Alpha-actinin-4,DKFZp686K23158,F actin cross linking protein,F-actin cross-linking protein,FSGS,FSGS 1,FSGS1,Focal segmental glomerulosclerosis 1,Non muscle alpha actinin 4,Non-muscle alpha-actinin 4,actinin 4,actinin4
- Application:
- IHC, WB
- Concentration:
- 0.8 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human ACTN4
- Uniprot:
- O43707
- Synonyms:
- ACTININ-4;alpha-actinin-4;focal segmental glomerulosclerosis 1;FSGS;FSGS1;non-muscle alpha-actinin 4
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.
- Shipping Conditions:
- Blue Ice