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E-AB-14736

CBR1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-14736
Additional Names:
15 hydroxyprostaglandin dehydrogenase [NADP+],15-hydroxyprostaglandin dehydrogenase [NADP+],CBR 1,CBR1,CRN,Carbonyl Reductase 1,Carbonyl reductase [NADPH] 1,NADPH dependent carbonyl reductase 1,NADPH-dependent carbonyl reductase 1,Prostaglandin 9 ket
Application:
IHC, WB
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human CBR1
Uniprot:
P16152
Synonyms:
15-hydroxyprostaglandin dehydrogenase;15-hydroxyprostaglandin dehydrogenase [NADP(+)];20-beta-hydroxysteroid dehydrogenase;carbonyl reductase (NADPH) 1;carbonyl reductase [NADPH] 1;CBR;epididymis secretory sperm binding protein;hCBR1;NADPH-dependent carbonyl reductase 1;PG-9-KR;prostaglandin 9-ketoreductase;prostaglandin-E(2) 9-reductase;SDR21C1;short chain dehydrogenase/reductase family 21C member 1
Extra Details:
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
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Blue Ice