E-AB-14694
PIM1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14694
- Additional Names:
- Oncogene PIM 1,Oncogene PIM1,PIM,PIM 1,PIM1,PIM3,Pim 1 kinase,Pim 1 oncogene,Pim2,Proto oncogene serine/threonine protein kinase Pim 1,Proto-oncogene ,pim 1 kinase 44 kDa isoform,pim 1 oncogene (proviral integration site 1),pim1 kinase 44 kDa isoform
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PIM1
- Uniprot:
- P11309
- Synonyms:
- Oncogene PIM1;PIM;pim-1 oncogene (proviral integration site 1);proto-oncogene serine/threonine-protein kinase pim-1;serine/threonine-protein kinase pim-1
- Extra Details:
- The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
- Shipping Conditions:
- Blue Ice