E-AB-14671
CBS Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14671
- Additional Names:
- AI047524,AI303044,Beta thionase,Beta-thionase,CBS,Cbs,Cbs cystathionine beta-synthase,Cystathionine beta synthase,Cystathionine beta-synthase,EC 4.2.1.22,HIP 4,HIP4,MGC18856,MGC18895,MGC37300,Methylcysteine synthase,OTTHUMP00000109416,OTTHUMP00000109418,S
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CBS
- Uniprot:
- P35520
- Synonyms:
- beta-thionase;CBS;CBSL;cystathionine beta-synthase;Cystathionine beta-synthase-like protein;HIP4;methylcysteine synthase;serine sulfhydrase
- Extra Details:
- The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.
- Shipping Conditions:
- Blue Ice