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E-AB-14668

REN Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-14668
Additional Names:
Angiotensin forming enzyme,Angiotensin forming enzyme precursor,Angiotensinogenase,Angiotensinogenase precursor,FLJ10761,HNFJ2,REN,RENI,Ren1,Renin,Renin precursor renal
Application:
IHC
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human REN
Uniprot:
P00797
Synonyms:
ADTKD4;angiotensin-forming enzyme;angiotensinogenase;HNFJ2;renin;renin precursor, renal;RTD
Extra Details:
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.
Shipping Conditions:
Blue Ice