E-AB-14601
ASL Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14601
- Additional Names:
- ARLY,ASAL,ASL,Argininosuccinase,Argininosuccinate lyase,Arginosuccinase,EC 4.3.2.1
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human ASL
- Uniprot:
- P04424
- Synonyms:
- argininosuccinase;argininosuccinate lyase;arginosuccinase;ASAL
- Extra Details:
- This gene encodes a member of the lyase 1 family.The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle.Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.A nontranscribed pseudogene is also located on the long arm of chromosome 22.Alternatively spliced transcript variants encoding different isoforms have been described.
- Shipping Conditions:
- Blue Ice