E-AB-14591
NOL3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14591
- Additional Names:
- ARC,Apoptosis repressor with CARD,MYC,MYP,Muscle enriched cytoplasmic protein,Muscle-enriched cytoplasmic protein,NOL3,NOP,Nol3,Nop30,Nucleolar protein 3,Nucleolar protein 3 (apoptosis repressor with CARD domain),Nucleolar protein of 30 kDa
- Application:
- IHC
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human NOL3
- Uniprot:
- O60936
- Synonyms:
- Apoptosis repressor with CARD;ARC;FCM;muscle-enriched cytoplasmic protein;MYOCL1;MYP;NOP;NOP30;nucleolar protein 3;nucleolar protein 3 (apoptosis repressor with CARD domain);nucleolar protein of 30 kDa
- Extra Details:
- This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.
- Shipping Conditions:
- Blue Ice