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E-AB-14538

ALDH8A1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-14538
Additional Names:
ALDH12,DJ352A20.2
Application:
IHC, WB
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human ALDH8A1
Uniprot:
Q9H2A2
Synonyms:
2-aminomuconic semialdehyde dehydrogenase;aldehyde dehydrogenase 12;aldehyde dehydrogenase family protein;ALDH12;DJ352A20.2
Extra Details:
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.
Shipping Conditions:
Blue Ice