E-AB-14487
ACVR2A Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14487
- Additional Names:
- ACTR 2,ACTR IIA,ACTR-IIA,ACTR2,ACTRII,ACTRIIA,ACVR2A,AVR2A,Activin A receptor type IIA,Activin receptor type 2A,Activin receptor type IIA,Activin receptor type-2A,Acvr 2,Acvr 2A,Acvr2,OTTHUMP00000197918
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human ACVR2A
- Uniprot:
- P27037
- Synonyms:
- activin A receptor, type IIA;Activin receptor type IIA;activin receptor type-2A;ACTRII;ACVR2
- Extra Details:
- This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
- Shipping Conditions:
- Blue Ice