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E-AB-14431

TYR Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-14431
Additional Names:
ATN,CMM8,LB24 AB,LB24-AB,Monophenol monooxygenase,OCA1,OCA1A,OCAIA,Oculocutaneous albinism IA,SHEP3,SK29 AB,SK29-AB,TYR,TYRO,Tumor rejection antigen AB,Tyrosinase,tyrosinase (oculocutaneous albinism IA)
Application:
IHC, WB
Concentration:
0.2 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human TYR
Uniprot:
P14679
Synonyms:
ATN;CMM8;LB24-AB;monophenol monooxygenase;OCA1;OCA1A;OCAIA;oculocutaneous albinism IA;SHEP3;SK29-AB;tumor rejection antigen AB;tyrosinase
Extra Details:
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Shipping Conditions:
Blue Ice