E-AB-14396
Factor IX Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14396
- Additional Names:
- Christmas Disease,Christmas factor,Coagulant factor IX,Coagulation factor 9,Coagulation factor IX,Coagulation factor IXa heavy chain,F9,FA9,FIX,Factor 9,Factor IX Deficiency,FactorIX,HEMB,Haemophilia B,MGC129641,MGC129642,P19,Plasma Thromboplastic Compone
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human F9
- Uniprot:
- P00740
- Synonyms:
- Christmas factor;coagulation factor IX;F9 p22;factor 9;factor IX F9;FIX;HEMB;P19;plasma thromboplastic component;plasma thromboplastin component;PTC;THPH8
- Extra Details:
- This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
- Shipping Conditions:
- Blue Ice