E-AB-14341
SH-PTP2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14341
- Additional Names:
- BPTP3,CFC,JMML,METCDS,MGC14433,NS1,OTTHUMP00000166107,OTTHUMP00000166108,PTN11,Protein tyrosine phosphatase 2,Protein tyrosine phosphatase 2C,Protein tyrosine phosphatase non receptor type 11,Protein-tyrosine phosphatase 1D,Protein-tyrosine phosphatase 2C
- Application:
- WB
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PTPN11
- Uniprot:
- Q06124
- Synonyms:
- BPTP3;CFC;JMML;METCDS;NS1;protein-tyrosine phosphatase 1D;protein-tyrosine phosphatase 2C;PTP-1D;PTP2C;SH-PTP2;SH-PTP3;SH2 domain-containing protein tyrosine phosphatase 2;SHP2;tyrosine-protein phosphatase non-receptor type 11
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice