E-AB-14316
RRM1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14316
- Additional Names:
- R1,Ribonucleoside diphosphate reductase M1 chain,Ribonucleoside diphosphate reductase large subunit,Ribonucleoside diphosphate reductase subunit M1,Ribonucleoside reductase,Ribonucleoside-di,Ribonucleoside-diphosphate reductase large subunit,large subunit
- Application:
- WB
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human RRM1
- Uniprot:
- P23921
- Synonyms:
- R1;ribonucleoside-diphosphate reductase large subunit;ribonucleoside-diphosphate reductase subunit M1;Ribonucleotide reductase large subunit;ribonucleotide reductase M1 polypeptide;ribonucleotide reductase, R1 subunit;RIR1;RR1
- Extra Details:
- This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
- Shipping Conditions:
- Blue Ice