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E-AB-14287

PDCD6 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-14287
Additional Names:
AIP1,ALG 2,ALG-2-interacting protein 1,ALG2,ALIX,Apoptosis linked gene 2,Apoptosis linked gene 2 protein,Apoptosis-linked gene 2 protein,FLJ42309,FLJ46208,Hp95,KIAA1375,MA 3,MA3,MGC111017,MGC119050,MGC9123,PDCD 6,PDCD6,PEF 1B,PEF1B,Pdcd6,Probable calcium
Application:
IHC, WB
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
ABP:
No Import Docs
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human PDCD6
Uniprot:
O75340
Synonyms:
ALG-2;ALG2;apoptosis-linked gene 2 protein homolog;PEF1B;probable calcium-binding protein ALG-2;programmed cell death protein 6
Extra Details:
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.
Shipping Conditions:
Blue Ice