E-AB-14280
PAK6 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14280
- Additional Names:
- CDKN1A activated kinase 6,EC 2.7.1.37,PAK 5,PAK 6,PAK-5,PAK-6,PAK5,PAK6,Pak6,Serine threonine protein kin,p21 activated protein kinase 6,p21 protein (Cdc42/Rac)-activated kinase 6,p21(CDKN1A) activated kinase 6,p21-activated kinase 6,p21activated kinase 6
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PAK6
- Uniprot:
- Q9NQU5
- Synonyms:
- p21 protein (Cdc42/Rac)-activated kinase 6;p21-activated kinase 6;p21(CDKN1A)-activated kinase 6;PAK-5;PAK-6;PAK5;PAK6;serine/threonine-protein kinase PAK 6
- Extra Details:
- This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice