E-AB-14218
MMP14 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14218
- Additional Names:
- Matrix metallopeptidase 14 (membrane inserted),Matrix metalloproteinase 14,Matrix metalloproteinase-14,Membrane type 1 matrix metalloproteinase,Membrane type 1 metalloprotease,Membrane type matrix metalloproteinase 1,Membrane-type matrix metalloproteinase
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human MMP14
- Uniprot:
- P50281
- Synonyms:
- matrix metallopeptidase 14 (membrane-inserted);matrix metalloproteinase-14;membrane type 1 metalloprotease;Membrane-type matrix metalloproteinase 1;membrane-type-1 matrix metalloproteinase;MMP-14;MMP-X1;MT-MMP;MT-MMP 1;MT1-MMP;MT1MMP;MTMMP1;WNCHRS
- Extra Details:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
- Shipping Conditions:
- Blue Ice