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E-AB-14217

MMP12 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-14217
Additional Names:
EC 3.4.24.65,HME,ME,MGC138506,MME,MMP 12,MMP-12,MMP12,Macrophage elastase,Macrophage metalloelastase,Macrophage metaloelastase,Matrix metallopeptidase 12 (macrophage elastase),Matrix metalloprotease 12,Matrix metalloproteinase-12,Mmp12
Application:
IHC
Concentration:
0.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human MMP12
Uniprot:
P39900
Synonyms:
HME;Macrophage elastase;macrophage metalloelastase;matrix metallopeptidase 12 (macrophage elastase);matrix metalloproteinase 12 (macrophage elastase);Matrix metalloproteinase-12;ME;MME;MMP-12
Extra Details:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin.
Shipping Conditions:
Blue Ice