E-AB-14181
KLK7 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14181
- Additional Names:
- Chymotryptic stratum corneum,KLK 7,KLK7,Kallikrein 7 (chymotryptic stratum corneum),Kallikrein related peptidase 7,Kallikrein-7,Kallikrein7,Klk7,PRSS 6,PRSS6,Protease serine 6,SCCE,Serine protease 6,Signal protein,Stratum corneum chymotrypt,hK 7,hK7,hSCCE
- Application:
- WB
- Concentration:
- 0.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human KLK7
- Uniprot:
- P49862
- Synonyms:
- hK7;kallikrein 7 (chymotryptic, stratum corneum);kallikrein-7;PRSS6;SCCE;serine protease 6;signal protein;stratum corneum chymotryptic enzyme
- Extra Details:
- This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
- Shipping Conditions:
- Blue Ice