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E-AB-14013

EMC8 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-14013
Additional Names:
C16orf2,C16orf4,COX4,COX4 neighbor,COX4AL,CX4NB,Cox4nb,ER membrane protein complex subunit 8,FAM158B,NOC4,Neighbor of COX4,Protein FAM158B,family with sequence similarity 158,member B,neighbor of
Application:
IHC, WB
Concentration:
0.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human EMC8
Uniprot:
O43402
Synonyms:
C16orf2;C16orf4;COX4 neighbor;COX4NB;ER membrane protein complex subunit 8;FAM158B;family with sequence similarity 158, member B;neighbor of COX4;NOC4;Protein FAM158B
Extra Details:
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Shipping Conditions:
Blue Ice