E-AB-13983
CCL4 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13983
- Additional Names:
- ACT2,AT744.1,G-26,HC21,LAG-1,LAG1,MIP-1-beta,MIP1B,MIP1B1,SCYA2,SCYA4
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CCL4
- Uniprot:
- P13236
- Synonyms:
- ACT2;AT744.1;AT744.2;C-C motif chemokine 4;C-C motif chemokine 4-like;CC chemokine ligand 4L1;CCL4L;chemokine (C-C motif) ligand 4;chemokine (C-C motif) ligand 4-like 1, telomeric;G-26;G-26 T-lymphocyte-secreted protein;HC21;LAG-1;LAG1;lymphocyte activation gene 1 protein;macrophage inflammatory protein 1-beta;macrophage inflammatory protein-1b2;MIP-1-beta;MIP-1-beta(1-69);MIP1B;MIP1B1;Monocyte adherence-induced protein 5-alpha;PAT 744;Protein H400;SCYA2;SCYA4;SCYA4L;SCYA4L1;SCYA4L2;secreted protein G-26;SIS-gamma;small inducible cytokine A4 (homologous to mouse Mip-1b);small inducible cytokine A4-like;Small-inducible cytokine A4;Small-inducible cytokine A4-like;T-cell activation protein 2
- Extra Details:
- The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
- Shipping Conditions:
- Blue Ice