E-AB-13974
Cathepsin E Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13974
- Additional Names:
- CATE,CTSE,Cathepsin E,Cathepsin E form II,Erythrocyte membrane aspartic proteinase,Slow moving proteinase
- Application:
- IHC, WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CTSE
- Uniprot:
- P14091
- Synonyms:
- CATE;cathepsin E;erythrocyte membrane aspartic proteinase;slow-moving proteinase
- Extra Details:
- The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
- Shipping Conditions:
- Blue Ice