E-AB-13956
Caldesmon Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13956
- Additional Names:
- CAD,CALD 1,CALD1,CDM,Caldesmon,Caldesmon 1,Caldesmon 1 Isoform 1,Caldesmon 1 Isoform 2,Caldesmon 1 Isoform 3,Caldesmon 1 Isoform 4,Caldesmon 1 Isoform 5,Caldesmon1,H CAD,HCAD,L CAD,LCAD,MGC21352,NAG22
- Application:
- IHC, WB
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human Caldesmo
- Uniprot:
- Q05682
- Synonyms:
- caldesmon;CDM;H-CAD;HCAD;L-CAD;LCAD;NAG22;testis secretory sperm-binding protein Li 227n
- Extra Details:
- This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. 
- Shipping Conditions:
- Blue Ice