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E-AB-13927

RAP1A Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-13927
Additional Names:
C21KG,G-22K,GTP-binding protein smg p21A,KREV1,RAP1A,Ras-related protein 1A,Ras-related protein Krev-1,Ras-related protein Rap-1A,SMGP21,member of RAS oncogene family
Application:
IHC
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human RAP1A
Uniprot:
P62834
Synonyms:
C21KG;G-22K;GTP-binding protein smg p21A;KREV-1;KREV1;RAP1;Ras-related protein Krev-1;ras-related protein Rap-1A;SMGP21
Extra Details:
The product of this gene belongs to the family of RAS-related proteins.These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common.The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins.The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.Two transcript variants encoding the same protein have been identified for this gene.
Shipping Conditions:
Blue Ice