E-AB-13876
IL18BP Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13876
- Additional Names:
- I18BP,IL18 BP,IL18 BPa,IL-18BP,IL18BPa,Interleukin 18 binding protein,Interleukin-18-binding protein,MC51L 53L 54L homolog gene product,Tadekinig alfa,Tadekinig-alfa,Tadekinig-alfa and IL18BP,IL18BP
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human IL18BP
- Uniprot:
- O95998
- Synonyms:
- FVH;IL18BPa;interleukin-18-binding protein;MC51L-53L-54L homolog gene product;tadekinig-alfa
- Extra Details:
- The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Shipping Conditions:
- Blue Ice