E-AB-13869
IL10RA Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13869
- Additional Names:
- IL-10R subunit,Interleukin-10 receptor subunit,IL-10R,IL10RA,CD210,CD210a,CDW210A,HIL-10R,IL-10R1,IL10R,IL-10 receptor subunit alpha,IL-10R subunit 1,IL-10R subunit alpha,IL-10RA,Interleukin-10 receptor subunit 1,Interleukin-10 receptor subunit alpha, IL-10R1, IL-10Ra,CDw210a antigen,HIL 10R,HIL10R,I10R1,IL 10R,IL 10R 1,IL 10R A,IL 10R1,IL10R1,Interleukin 10 receptor alpha,Interleukin 10 receptor alpha chain
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human IL10RA
- Uniprot:
- Q13651
- Synonyms:
- CD210;CD210a;CDW210A;HIL-10R;IL-10 receptor subunit alpha;IL-10R subunit 1;IL-10R subunit alpha;IL-10R1;IL-10RA;IL10R;interleukin 10 receptor, alpha;interleukin-10 receptor alpha chain;interleukin-10 receptor subunit 1;interleukin-10 receptor subunit alpha
- Extra Details:
- The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
- Shipping Conditions:
- Blue Ice