BAK1 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-13862
Additional Names:: Apoptosis regulator BAK,BAK,BAK like,BCL2 antagonist/killer 1,BCL2L7,Bak NT,Bak1,Bcl 2 homologous antagonist/killer,Bcl 2 like 7 protein,Bcl-2 homologous antagonist/killer,Bcl-2-like protein 7,Bcl2 like 7 Protein,Bcl2-L-7,CDN1,Cell death inhibitor 1,M
Application:: WB
Concentration:: 0.3 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human BAK1
Uniprot:: Q16611
Synonyms:: apoptosis regulator BAK;BAK;BAK-LIKE;bcl-2 homologous antagonist/killer;bcl-2-like protein 7;bcl2-L-7;BCL2-like 7 protein;BCL2L7;CDN1;pro-apoptotic protein BAK
Extra Details:: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.