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E-AB-13801

ALDH1A1/2/3 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-13801
Additional Names:
ALDC,ALDH-E1,ALDH1,ALDH11,ALDH1A6,ALDH6,PUMB1,RALDH(II),RALDH1,RALDH2,RALDH2-T,RALDH3
Application:
IHC, WB
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human ALDH1A1/ALDH1A2/ALDH1A3
Uniprot:
O94788, P00352, P47895
Synonyms:
acetaldehyde dehydrogenase 1;acetaldehyde dehydrogenase 6;ALDC;aldehyde dehydrogenase 1, soluble;aldehyde dehydrogenase 6;Aldehyde dehydrogenase family 1 member A1;Aldehyde dehydrogenase family 1 member A2;aldehyde dehydrogenase family 1 member A3;Aldehyde dehydrogenase, cytosolic;aldehyde dehydrogenase, liver cytosolic;ALDH class 1;ALDH-E1;ALDH1;ALDH11;ALDH1A6;ALDH6;ALHDII;epididymis luminal protein 12;epididymis luminal protein 9;epididymis secretory sperm binding protein Li 53e;HEL-9;HEL-S-53e;HEL12;MCOP8;PUMB1;RALDH 1;RALDH 2;RALDH(II);RALDH1;RALDH2;RALDH2-T;RALDH3;retinal dehydrogenase 1;retinal dehydrogenase 2;retinaldehyde dehydrogenase 1;retinaldehyde dehydrogenase 3;retinaldehyde-specific dehydrogenase type 2
Extra Details:
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
Shipping Conditions:
Blue Ice