E-AB-13740
TMPRSS11F Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13740
- Additional Names:
- Airway trypsin-like protease 4,TMPRSS11F,Transmembrane protease serine 11F
- Application:
- IHC, WB
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human TMPRSS11F
- Uniprot:
- Q6ZWK6
- Synonyms:
- airway trypsin-like protease 4;HATL4;transmembrane protease serine 11F;transmembrane protease, serine 11F
- Extra Details:
- TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
- Shipping Conditions:
- Blue Ice