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E-AB-13736

TM7SF2 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-13736
Additional Names:
ANG1,DHCR14A,NET47
Application:
WB
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human TM7SF2
Uniprot:
O76062
Synonyms:
3-beta-hydroxysterol Delta (14)-reductase;ANG1;another new gene 1 protein;C-14 sterol reductase;C14SR;delta-14-SR;delta(14)-sterol reductase TM7SF2;DHCR14A;NET47;putative sterol reductase SR-1;sterol C14-reductase;Transmembrane 7 superfamily member 2
Extra Details:
Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.
Shipping Conditions:
Blue Ice