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E-AB-13723

TBC1D4 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-13723
Additional Names:
AS 160,AS160,Acrg embryonic lethality (mouse) minimal region ortholog,Acrg embryonic lethality minimal region ortholog,Acrg embryonic lethality mouse minimal region ortholog,Akt substrate of 160 kDa,BUB2,CDC16,KIAA0603,NIDDM5,TBC (Tre 2 BUB2 CDC16) domain
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human TBC1D4
Uniprot:
O60343
Synonyms:
akt substrate of 160 kDa;AS160;NIDDM5;TBC (Tre-2, BUB2, CDC16) domain-containing protein;TBC1 domain family member 4
Extra Details:
TBC1 domain family member 4 (TBC1D4), also designated AS160, can be insulin- and/or AKT1-induced. Insulin-stimulated phosphorylation is required for GLUT4 translocation. TBC1D4 may play a role as a GTPase activating protein for proteins in the Rab family. It is expressed primarily in skeletal muscle and heart, as well as spleen, lymph node and leukocytes. Defects in the TBC1D4 gene may cause atopic dermatitis (AD), sometimes referred to as eczema, an atopic chronic skin disease. The skin of affected individuals reacts to irritants or allergens and becomes red, flaky and itchy. The skin is also more vulnerable to inflammations, and symptoms can grow or disappear over time.
Shipping Conditions:
Blue Ice