E-AB-13684
ROR1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13684
- Additional Names:
- Inactive tyrosine protein kinase transmembrane receptor ROR1,MGC99659,NTRKR1,Neurotrophic tyrosine kinase,Neurotrophic tyrosine kinase receptor related 1,OTTHUMP00000010573,OTTHUMP00000010574,OTTM,dJ537F10.1,receptor related 1
- Application:
- IHC
- Concentration:
- 0.9 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ROR1
- Uniprot:
- Q01973
- Synonyms:
- dJ537F10.1;inactive tyrosine-protein kinase transmembrane receptor ROR1;neurotrophic tyrosine kinase, receptor-related 1;NTRKR1
- Extra Details:
- This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice