E-AB-13450
UHRF2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13450
- Additional Names:
- DKFZp434B0920,DKFZp686G0837,E3 ubiquitin-protein ligase UHRF2,MGC33463,Np95 like RING finger protein,Np95-like ring finger protein,Np95/ICBP90 like RING finger protein,Np95/ICBP90-like RING finger protein,Nuclear protein 97,Nuclear zinc finger protein Np9
- Application:
- IHC
- Concentration:
- 0.8 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human UHRF2
- Uniprot:
- Q96PU4
- Synonyms:
- E3 ubiquitin-protein ligase UHRF2;NIRF;Np95-like ring finger protein;np95/ICBP90-like RING finger protein;nuclear protein 97;nuclear zinc finger protein NP97;RING finger protein 107;RING-type E3 ubiquitin transferase UHRF2;RNF107;TDRD23;ubiquitin-like PHD and RING finger domain-containing protein 2;ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase;ubiquitin-like-containing PHD and RING finger domains protein 2;ubiquitin-like, containing PHD and RING finger domains, 2;URF2
- Extra Details:
- This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
- Shipping Conditions:
- Blue Ice