E-AB-13437
NLRP4 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13437
- Additional Names:
- CLR19.5,CT58,Cancer/testis antigen 58,FLJ32126,LRR and PYD containing protein 4,LRR and PYD domains-containing protein 4,NACHT,NALP4,NLR family,NLRP4,Nucleotide binding oligome,leucine rich repeat and PYD containing 4,pyrin domain containing 4
- Application:
- IHC
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human NLRP4
- Uniprot:
- Q96MN2
- Synonyms:
- cancer/testis antigen 58;CLR19.5;CT58;NACHT, leucine rich repeat and PYD containing 4;NACHT, LRR and PYD domains-containing protein 4;NALP4;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4;PAAD and NACHT-containing protein 2;PAN2;PYPAF4;PYRIN and NACHT-containing protein 2;PYRIN-containing APAF1-like protein 4;ribonuclease inhibitor 2;RNH2
- Extra Details:
- NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes
- Shipping Conditions:
- Blue Ice