MAGEL2 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-13399
Additional Names:: MAGE-like 2,MAGE-like protein 2,MAGEL2,Mage-l2,NDNL1,Necdin like protein 1,PWLS,Protein nM15,melanoma antigen-like gene 2,nM15,necdin-like 1,ns7
Application:: IHC
Concentration:: 0.8 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human MAGEL2
Uniprot:: Q9UJ55
Synonyms:: MAGE-like protein 2;melanoma antigen family L2;NDNL1;necdin-like protein 1;nM15;protein nM15;PWLS;SHFYNG
Extra Details:: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.