E-AB-13381
LIMK1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13381
- Additional Names:
- EC 2.7.1.37,LIM domain containing protein kinase,LIM domain kinase 1,LIM kinase,LIM motif containing protein kinase,LIMK,LIMK 1,LIMK-1,LIMK1,limk1
- Application:
- IHC
- Concentration:
- 0.9 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human LIMK1
- Uniprot:
- P53667
- Synonyms:
- LIM domain kinase 1;LIM motif-containing protein kinase;LIMK;LIMK-1
- Extra Details:
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure.
- Shipping Conditions:
- Blue Ice