E-AB-13360
KDM5B Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13360
- Additional Names:
- CT31,Cancer/testis antigen 31,Histone demethylase JARID1B,JARID1B,Jumonji AT rich interactive domain 1B,Jumonji/ARID domain-containing protein 1B,KDM5B,Kdm5b,Lysine (K) specific demethylase 5B,Lysine demethylase 5B,Lysine specific demethylase 5B,Lysine-sp
- Application:
- IHC
- Concentration:
- 1.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human KDM5B
- Uniprot:
- Q9UGL1
- Synonyms:
- [histone H3]-trimethyl-L-lysine(4) demethylase 5B;cancer/testis antigen 31;CT31;histone demethylase JARID1B;JARID1B;jumonji, AT rich interactive domain 1B;jumonji/ARID domain-containing protein 1B;lysine (K)-specific demethylase 5B;lysine-specific demethylase 5B;MRT65;PLU-1;PLU1;PPP1R98;protein phosphatase 1, regulatory subunit 98;PUT1;putative DNA/chromatin binding motif;RBBP2H1A;RBP2-H1;retinoblastoma-binding protein 2 homolog 1;retinoblastoma-binding protein 2, homolog 1A
- Extra Details:
- PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
- Shipping Conditions:
- Blue Ice