E-AB-13288
ZNF395 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13288
- Additional Names:
- DKFZp434K1210,HD gene regulatory region binding protein 2,HD gene regulatory region-binding protein 2,HD-regulating factor 2,HDBP-2,HDBP2,HDRF-2,Huntington disease gene regulatory region-binding protein 2,Huntington's disease gene regulatory region bindin
- Application:
- IHC
- Concentration:
- 0.8 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ZNF395
- Uniprot:
- Q9H8N7
- Synonyms:
- HD gene regulatory region-binding protein 2;HD-regulating factor 2;HDBP-2;HDBP2;HDRF-2;huntington disease gene regulatory region-binding protein 2;Huntington's disease gene regulatory region-binding protein 2;papillomavirus regulatory factor 1;papillomavirus regulatory factor PRF-1;papillomavirus-binding factor;PBF;PRF-1;PRF1;Si-1-8-14;zinc finger protein 395
- Extra Details:
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3'-CCGG-5' sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.
- Shipping Conditions:
- Blue Ice