DSC2 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-13194
Additional Names:: ARVD11,CDHF2,Cadherin family member 2,DG2,DGII/III,DKFZp686I11137,DS,DSC 2,DSC2,Desmocollin 3,Desmocollin-2,Desmocollin-3,Desmocollin2,Desmosomal glycoprotein II,Desmosomal glycoprotein II and III,Desmosomal glycoprotein II/III,Desmosomal glycoprotein III
Application:: IHC
Concentration:: 0.7 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human DSC2
Uniprot:: Q02487
Synonyms:: ARVD11;cadherin family member 2;CDHF2;desmocollin-2;Desmocollin-3;Desmosomal glycoprotein II;desmosomal glycoprotein II/III;Desmosomal glycoprotein III;DG2;DGII/III;DSC3
Extra Details:: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.