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E-AB-13182

DAAM1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-13182
Additional Names:
DAAM 1,Dishevelled associated activator of morphogenesis 1,FLJ41657,KIAA0666
Application:
IHC, WB
Concentration:
1.2 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human DAAM1
Uniprot:
Q9Y4D1
Synonyms:
disheveled-associated activator of morphogenesis 1
Extra Details:
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes.The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity.A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement.The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex.
Shipping Conditions:
Blue Ice