E-AB-13122
NCR2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13122
- Additional Names:
- Activating NK receptor NKp44,CD336,CD336 antigen,LY95,Lymphocyte antigen 95,Lymphocyte antigen 95 (activating NK receptor,Lymphocyte antigen 95 homolog,Lymphocyte antigen 95 homolog (activating NK receptor,NK p44),Natur,dJ149M18.1,homolog of,mouse
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human NCR2
- Uniprot:
- O95944
- Synonyms:
- CD336;dJ149M18.1;LY95;lymphocyte antigen 95 (activating NK-receptor; NK-p44);Lymphocyte antigen 95 homolog;lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44);natural cytotoxicity triggering receptor 2;natural killer cell p44-related protein;NK cell activating receptor (NKp44);NK cell-activating receptor;NK-p44;NKP44
- Extra Details:
- Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene.NCR2 has also been designated as CD336 (cluster of differentiation 336).NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis.NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain.Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level.A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.
- Shipping Conditions:
- Blue Ice