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E-AB-13070

SNCA Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-13070
Additional Names:
Alpha synuclein,Alpha-synuclein,MGC105443,MGC110988,MGC127560,MGC64356,NACP,No,Non A beta component of AD amyloid,Non A4 component of amyloid,Non A4 component of amyloid precursor,Non-A beta component of AD amyloid,alphaSYN,isoform NACP140
Application:
IHC
Concentration:
0.1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human SNCA
Uniprot:
P37840
Synonyms:
alpha-synuclein;I+/--synuclein;NACP;non A-beta component of AD amyloid;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor;PARK1;PARK4;PD1;synuclein alpha-140;synuclein, alpha (non A4 component of amyloid precursor);truncated alpha synuclein
Extra Details:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Shipping Conditions:
Blue Ice