E-AB-13026
PFKFB1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13026
- Additional Names:
- F6PK,HL2K,PFRX
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PFKFB1
- Uniprot:
- P16118
- Synonyms:
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1;6PF-2-K/Fru-2,6-P2ase 1;6PF-2-K/Fru-2,6-P2ASE liver isozyme;F6PK;fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase;HL2K;PFK/FBPase 1;PFRX
- Extra Details:
- This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
- Shipping Conditions:
- Blue Ice