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E-AB-13005

PIAS2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-13005
Additional Names:
ARIP3,Androgen receptor interacting protein 3,Androgen receptor-interacting protein 3,DAB2 interacting protein,DAB2-interacting protein,DIP,E3 SUMO protein ligase PIAS2,E3 SUMO-protein ligase PIAS2,MIZ,Miz1,Msx interacting zinc finger protein,Msx-interact
Application:
IHC
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human PIAS2
Uniprot:
O75928
Synonyms:
androgen receptor-interacting protein 3;ARIP3;DAB2-interacting protein;DIP;E3 SUMO-protein ligase PIAS2;E3 SUMO-protein transferase PIAS2;MIZ1;msx-interacting zinc finger protein;PIAS-NY protein;PIASX;protein inhibitor of activated STAT X;Protein inhibitor of activated STAT2;SIZ2;zinc finger, MIZ-type containing 4;ZMIZ4
Extra Details:
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family.PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor.A pseudogene of this gene is located on the short arm of chromosome 4.The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
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