E-AB-13000
UPF1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-13000
- Additional Names:
- ATP dependent helicase RENT1,ATP-dependent helicase RENT1,Delta helicase,FLJ43809,FLJ46894,HUPF 1,KIAA0221,NORF 1,NORF1,Nonsense mRNA reducing factor 1,RENT 1,RENT1,Regulator of nonsense transcripts 1,Smg 2,Smg 2 homolog nonsens,hUpf1,pNORF 1,pNORF1
- Application:
- IHC, WB
- Concentration:
- 0.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human UPF1
- Uniprot:
- Q92900
- Synonyms:
- ATP-dependent helicase RENT1;delta helicase;HUPF1;nonsense mRNA reducing factor 1;NORF1;pNORF1;regulator of nonsense transcripts 1;RENT1;smg-2;smg-2 homolog, nonsense mediated mRNA decay factor;up-frameshift mutation 1 homolog;up-frameshift suppressor 1 homolog;UPF1 regulator of nonsense transcripts homolog;UTF;yeast Upf1p homolog
- Extra Details:
- This gene encodes a protein that is part of a post-splicing multiprotein complex involved in botHuman, MouseRNA nuclear export and mRNA surveillance.mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons.This protein is located only in the cytoplasm.When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.Use of multiple polyadenylation sites has been noted for this gene.
- Shipping Conditions:
- Blue Ice