E-AB-12915
TRPM5 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12915
- Additional Names:
- 9430099A16Rik,LTrpC-5,LTrpC5,Long transient receptor potential channel 5,MLSN1 and TRP related gene 1,MLSN1 and TRP related gene 1 protein,MLSN1 and TRP-related,MLSN1- and TRP-related gene 1 protein,MTR1,Novel protein similar to vertebrate transient recep
- Application:
- IHC, WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human TRPM5
- Uniprot:
- Q9NZQ8
- Synonyms:
- long transient receptor potential channel 5;LTRPC5;MLSN1 and TRP-related;MLSN1- and TRP-related gene 1 protein;MTR1;transient receptor potential cation channel subfamily M member 5
- Extra Details:
- This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
- Shipping Conditions:
- Blue Ice