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E-AB-12907

TEK Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-12907
Additional Names:
Angiopoietin 1 receptor,Angiopoietin-1 receptor,CD202b,CD202b antigen,Endothelial tyrosine kinase,Endothelium specific receptor tyrosine kinase 2,Hyk,Soluble TIE2 variant 1,Soluble TIE2 variant 2,TEK tyrosine ,Tek,hTIE 2,hTIE2,p140 TEK,tek tyrosine kinase
Application:
IHC
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human TEK
Uniprot:
Q02763
Synonyms:
angiopoietin-1 receptor;CD202B;endothelial tyrosine kinase;GLC3E;p140 TEK;TEK tyrosine kinase, endothelial;TIE-2;TIE2;tunica interna endothelial cell kinase;tyrosine kinase with Ig and EGF homology domains-2;tyrosine-protein kinase receptor TEK;tyrosine-protein kinase receptor TIE-2;VMCM;VMCM1
Extra Details:
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smootHuman, Mouseuscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Shipping Conditions:
Blue Ice