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E-AB-12884

AKAP12 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12884
Additional Names:
A kinase (PRKA) anchor protein (gravin) 12,A kinase Anchor Protein 12,A kinase anchor protein 250kDa,A-kinase anchor protein 12,A-kinase anchor protein 250 kDa,AKA12,AKAP 12,AKAP 250,AKAP-12,AKAP250,Akap12,DKFZp686M0430,DKFZp686O0331,FLJ20945,FLJ97621,Ger
Application:
IHC
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human AKAP12
Uniprot:
Q02952
Synonyms:
A kinase (PRKA) anchor protein 12;A-kinase anchor protein 12;A-kinase anchor protein 250 kDa;A-kinase anchor protein, 250kDa;AKAP 250;AKAP250;Gravin;kinase scaffold protein gravin;Myasthenia gravis autoantigen;myasthenia gravis autoantigen gravin;Src-Suppressed C Kinase Substrate;SSeCKS
Extra Details:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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Blue Ice