E-AB-12879
PLAT Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12879
- Additional Names:
- Alteplase,DKFZp686I03148,PLAT,Plasminogen activator tissue,Plasminogen activator tissue type,Reteplase,T Plasminogen Activator,T-plasminogen activator,Tissue plasminogen activator (t PA),Tissue type plasminogen activator,Tissue-type plasminogen,t PA,t-PA
- Application:
- IHC, WB
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PLAT
- Uniprot:
- P00750
- Synonyms:
- alteplase;plasminogen/activator kringle;reteplase;T-PA;t-plasminogen activator;tissue-type plasminogen activator;TPA
- Extra Details:
- This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice